Uridine phosphorylase from Hymenolepis diminuta (Cestoda): kinetics and inhibition by pyrimidine nucleoside analogs.

Effect of age of the intermediate host Tribolium confusum (Coleoptera) on infection by Hymenolepis diminuta (Cestoda).

A cross-sectional study of 27 cohorts of Tribolium confusum aged 2-78 wk was done to examine effects of host age on exposure to eggs of Hymenolepis diminuta under standardized conditions. Pre-exposure, fasting, and postexposure mortality were low, sex ratio was equal, and fecundity of hosts was high during the first 30 wk, followed by increasing mortality and male bias of the sex ratio, and dec...

Studies on Malic Enzyme from Hymenolepis Diminuta

Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.

Uridine-cytidine kinases (UCK) have important roles for the phosphorylation of nucleoside analogs that are being investigated for possible use in chemotherapy of cancer. We have cloned the cDNA of two human UCKs. The approximately 30-kDa proteins, named UCK1 and UCK2, were expressed in Escherichia coli and shown to catalyze the phosphorylation of Urd and Cyd. The enzymes did not phosphorylate d...

Phosphorylation of Uridine and Cytidine Nucleoside Analogs by Two Human Uridine-Cytidine Kinases

Uridine-cytidine kinases (UCK) have important roles for the phosphorylation of nucleoside analogs that are being investigated for possible use in chemotherapy of cancer. We have cloned the cDNA of two human UCKs. The '30-kDa proteins, named UCK1 and UCK2, were expressed in Escherichia coli and shown to catalyze the phosphorylation of Urd and Cyd. The enzymes did not phosphorylate deoxyribonucle...

Therapeutic efficacy of Zanthoxylum rhetsa DC extract against experimental Hymenolepis diminuta (Cestoda) infections in rats.

Zanthoxylum rhetsa DC (Rutaceae), commonly called prickly ash, is used in the folk medicine of Naga tribes in India as a deworming remedy. In the present study, the therapeutic efficacy of Z. rhetsa leaf extract was investigated against experimental Hymenolepis diminuta (Cestoda) infections in albino rats. The efficacy of extract was determined on the basis of reduction in the eggs per gram of ...